Non-Protein Coding RNAs (Springer Series in Biophysics) (by Nils Walter, Sarah A. Woodson, Robert T. Batey)


Author(s): Nils Walter, Sarah A. Woodson, Robert T. Batey

Publisher: Springer
Publish date: 2008-12-05
ISBN-10: 3540708332
ISBN-13: 9783540708339
Language: English
Description: The 2006 Nobel Prize in Physiology or Medicine was awarded to the
discoverers of RNA interference, Andrew Fire and Craig Mello. This
prize, which follows “RNA” Nobels for splicing and RNA catalysis,
highlights just one class of recently discovered non-protein coding
RNAs. Remarkably, non-coding RNAs are thought to outnumber protein
coding genes in mammals by perhaps as much as four-fold. In fact,
it appears that the complexity of an organism correlates with the
fraction of its genome devoted to non-protein coding RNAs.
Essential biological processes as diverse as cell differentiation,
suppression of infecting viruses and parasitic tra- posons,… more…

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